- Office Supplies, Equipment & Office Furniture Stores, Jacksonville
- Oil Change & Lubrication, Jacksonville - Auto Oil & Quick Lube
- Ophthalmologists, Jacksonville - Eye Doctors, Physicians & Surgeons (Ophthalmology)
- Optical Goods Repair & Service, Jacksonville - Camera Repair
- Optical Stores - Eyeglasses, Lenses & Sunglasses, Jacksonville
- Opticians, Jacksonville
- Optometrists, Jacksonville - Eye Doctors, Physicians & Surgeons (Optometry)
- Oriental Food Products, Jacksonville
- Oriental Goods & Products Stores, Jacksonville
- Ornamental Iron - Residential, Jacksonville - Wrought Iron Work Supplies, Parts, Gates, Railings, Stairs, Spirals, Fence, etc
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- Ornamental Metal Work, Jacksonville - Steel, Iron, Bronze, etc
- Ornamental Nursery, Jacksonville
- Ornamental Nursery Services, Jacksonville
- Orthodontist, Jacksonville - Teeth Straightening, Invisalign & Dental Braces
- Other Building Materials & Supplies, Jacksonville
- Other Lodging, Jacksonville
- Outdoor & Lawn & Garden Equipment Repair & Service, Jacksonville
- Outdoor Equipment & Accessories, Jacksonville
- Overhead Door, Jacksonville
- Oxygen & Respiratory Equipment & Supplies, Jacksonville - Oxygen Concentrator, Tank, Machine, etc
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